Dr. Agnew is a noted "ExtroVET." She graduated from Auburn University College of Veterinary Medicine in 2013. Prior to obtaining her DVM degree, she earned a bachelor's degree in Animal and Dairy Science at Auburn University. Dr. Agnew owns her own veterinary relief business, which she started in 2019. She is also active in organized veterinary medicine. Dr. Agnew currently serves as both the Secretary and Treasurer of the Madison County Veterinary Medical Association, the representative for the local association to the Alabama Veterinary Medical Assocation, and as a member of the Alabama Veterinary Medical Association's Legislative Committee. In her spare time, she enjoys hiking, running, traveling, planning travel, and rock climbing. She has run a 50k race and been to all 50 states.

Shelby Agnew has been a guest on 2 episodes.